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Creative Biogene Gene Family Offers Professional Support for Gene Identification and Disease Treatment

Creative Biogene, a leading biotechnology product and services provider, recently announces the professional support of gene families. As part of a hierarchy of information storage in a genome, gene families play a vital function in the evolution and diversity of multicellular organisms, which can offer backup for researchers to predict the function of newly identified genes based on the similarity to known genes, furthermore, applying in the treatment of various diseases.

New York, Oct 22th, 2018 - Creative Biogene, a leading biotechnology product and services provider, recently announces the professional support of gene families. As part of a hierarchy of information storage in a genome, gene families play a vital function in the evolution and diversity of multicellular organisms, which can offer backup for researchers to predict the function of newly identified genes based on the similarity to known genes, furthermore, applying in the treatment of various diseases.

Creative Biogene provides a platform for displaying information about specific gene families to make it convenient for researchers to choose the gene family that suits the needs:

GPCR Family, as one of the key members in our gene family, representing the largest family of proteins in the human proteome. It involves a common structure of seven transmembrane helices and can be divided into five major categories and are further divided into subfamilies based on sequence similarity. GPCR-mediated signaling pathways are associated with many human diseases, at present, it remains the main source of new drugs and is the focus of extensive research work in academia and the pharmaceutical industry. Pharmacological parameters with new research will contribute to the more selective role of drugs in GPCRs, while the dimensions include biased ligands, allosteric modulators, receptor antibodies, residence time, multi pharmacology, and pharmacogenomics of GPCRs. Characterization of these parameters for new compounds is expected to be a more efficient method of discovering GPCR drugs with fewer side effects.

Currently, the recognized victory in immunotherapy is the development of neutralizing antibodies and Fc fusion proteins. Due to the primary function of TNF superfamily molecules is to regulate cell survival, and the inhibition of these interactions prevents activation of downstream signaling pathways in TNFR, thereby minimizing proinflammatory processes that initiate and reduce autoimmune and inflammatory pathologies in immune cells. There is increasing evidence that many TNF superfamily molecules play vital roles in immune regulation, immune-mediated diseases and cancer.

‘In fact, ongoing preclinical studies and promising early clinical results to indicate that targeting the TNFL / TNFR axis will be part of the clinical practice in the near future.’ said Wendy Wilson, the marketing director of Creative Biogene, she also claimed that ‘However, ubiquitous pro-apoptotic or costimulatory TNFR signaling may have serious side effects. Therefore, tumor-restricted activation is underway to take full advantage of the therapeutic potential of this regulatory axis.’

Except for the above-mentioned gene family, Creative Biogene also provides other gene families for biotechnology development and disease treatment, which are mainly included as follows:

. Immunoglobulin Superfamily

. TRP Ion Channel Family

. Kir Channel Family

. Nuclear Receptor Superfamily

All of these gene family are available on Creative Biogene, they can fully support for gene identification and various disease treatment.

About Creative Biogene

Founded in 2005, Creative Biogene provides researchers with innovative biotechnology products and services to greatly enhance the final result though exploring biology-related issues and gene discovery. Creative Biogene is a well-recognized industry leader with more than 10 years experience and support researchers worldwide. 

Media Contact
Company Name: Creative Biogene
Contact Person: Wendy Wilson
Email: Send Email
Phone: 6316197922
Address:45-1 Ramsey Road
City: Shirley
State: New York
Country: United States
Website: https://www.creative-biogene.com



Source: www.abnewswire.com

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