FORM 6-K

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D. C. 20549



                        Report of Foreign Private Issuer
                      Pursuant to Rule 13a-16 or 15d-16 of
                       the Securities Exchange Act of 1934

                         For the month of November 2005

                                 DRYSHIPS, INC.

                               80 Kifissias Avenue
                        Amaroussion 15125, Athens Greece
                    (Address of principal executive offices)

     Indicate by check mark whether the registrant files or will file annual
reports under cover Form 20-F or Form 40-F.

                           Form 20-F [X] Form 40-F [_]

     Indicate by check mark whether the registrant by furnishing the information
contained in this Form is also thereby furnishing the information to the
commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

                                 Yes [_] No [X]



INFORMATION CONTAINED IN THIS FORM 6-K REPORT

Attached hereto as Exhibit 1 is a copy of the press release issued by DryShips,
Inc. on November 21, 2005.

                                                                Exhibit 1




                           DRYSHIPS TO PRESENT AT THE
                  GOLDMAN SACHS 2ND ANNUAL SHIPPING CONFERENCE
                    IN NEW YORK ON TUESDAY, NOVEMBER 29, 2005

ATHENS, Greece, November 21, 2005 - DryShips Inc. (NASDAQ: DRYS) announced today
that on Tuesday, November 29, 2005, George Economou Chairman & Chief Executive
Officer, will be presenting at the Goldman Sachs 2nd Annual Shipping Conference
to be held on that day at the Goldman Sachs Conference Center in New York City.

Furthermore, as already announced, on Friday, December 2, 2005, George Economou
Chairman & Chief Executive Officer, and Chris Thomas, the Company's Chief
Financial Officer will be presenting at an analyst and investor meeting to be
held that day at the Harvard Club in New York City at 12:00 PM EST.

About DryShips Inc.
DryShips Inc., based in Greece, is an owner and operator of drybulk carriers
that operate worldwide. As of the day of this Release, DryShips owns a fleet of
27 drybulk consisting 4 Capesize, 21 Panamax and 2 Handymax vessels, with a
combined deadweight tonnage of approximately 2.3 million. DryShips is the second
largest Panamax operator in the world.

DryShips Inc.'s common stock is listed on NASDAQ National Market where it trades
under the symbol "DRYS".

                      Visit our website at www.dryships.com
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Company Contact:
Christopher J. Thomas
Chief Financial Officer
DryShips Inc.
Tel. 011-30-210-809-0570 
E-mail: management@dryships.com

Investor Relations / Media:
Nicolas Bornozis
Capital Link, Inc. (New York)
Tel. 212-661-7566 
E-mail: nbornozis@capitallink.com


                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.


                                 DryShips, Inc.
                          ---------------------------------
                                  (Registrant)


Dated:  November 21, 2005               By /s/ Christopher Thomas
                                        ----------------------------------
                                        Christopher Thomas
                                        Chief Financial Officer



23113.0002 #620496