FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * HYDE JOSEPH R III   2. Issuer Name and Ticker or Trading Symbol GTX INC /DE/ [GTXI] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 175 TOYOTA PLAZA, 7TH FLOOR 3. Date of Earliest Transaction (Month/Day/Year) 07/01/2011 (Street) MEMPHIS, TN 38103 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 07/01/2011   A   1,722.34 A $ 4.79 10,941,802.11 (1) D   Common Stock               808,169 (2) I By 2010-1 GRAT Common Stock               161,633 (3) I By 2010-2 GRAT Common Stock               769,830 I By 2009-4 GRAT Common Stock               153,966 I By 2009-5 GRAT Common Stock               216,462 I By Spouse Common Stock               410,325 I By Trust Common Stock               410,324 I By Trust Common Stock               410,324 I By Trust Common Stock               144,645 I By Trust Common Stock               114,350 I By Trust Common Stock               91,628 I By Pittco Associates, L.P. Common Stock               3,915,716 I By Pittco Investments, L.P.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
HYDE JOSEPH R III 175 TOYOTA PLAZA 7TH FLOOR MEMPHIS, TN 38103	X	X

Signatures

/s/ Henry P. Doggrell, by Power of Attorney		07/05/2011
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Includes a distribution of 191,831 shares from the 2010-1 Grantor Retained Annuity Trust on June 15, 2011, and a distribution of 38,367 shares from the 2010-2 Grantor Retained Annuity Trust on June 15, 2011 to the reporting person and represents a change in beneficial ownership.
(2)	Excludes the distribution of 191,831 shares from the 2010-1 Grantor Retained Annuity Trust to the reporting person on June 15, 2011 and represents a change in beneficial ownership.
(3)	Excludes the distribution of 38,367 shares from the 2010-2 Grantor Retained Annuity Trust to the reporting person on June 15, 2011 and represents a change in beneficial ownership.

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