Ownership Submission
FORM 5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Form 3 Holdings Reported
Form 4 Transactions Reported
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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1. Name and Address of Reporting Person *
PESEC JOHN A
 2. Issuer Name and Ticker or Trading Symbol
KEITHLEY INSTRUMENTS INC [KEI] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
VP Worldwide Sales & Support
(Last)
(First)
(Middle)

KEITHLEY INSTRUMENTS, INC., 28775 AURORA ROAD		 3. Statement for Issuer's Fiscal Year Ended (Month/Day/Year)
09/30/2007
(Street)


SOLON, OH 44139		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Reporting
(check applicable line)

_X_ Form Filed by One Reporting Person
___ Form Filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned at end of Issuer's Fiscal Year
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Amount (A) or (D) Price
Common Shares 03/30/2007   J(1) 17 A $ 15.1899 7,107 D  
Common Shares 06/29/2007   J(1) 21 A $ 12.6769 7,128 D  
Common Shares 09/28/2007   J(1) 26 A $ 10.5994 7,154 D  
Common Shares             10 I Jointly held with wife
Common Shares             9 I Wife

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 2270 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
(A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Common Share Option $ 2.5313           09/12/2000 09/11/2008 Common Shares
5,000
  5,000
D
 
Common Share Option $ 4.125           07/17/2001 07/16/2009 Common Shares
12,000
  12,000
D
 
Common Share Option $ 45.125           08/02/2002(2) 08/01/2010 Common Shares
11,000
  11,000
D
 
Common Share Option $ 18.41           07/25/2003(3) 07/24/2011 Common Shares
25,000
  25,000
D
 
Common Share Option $ 13.76           07/24/2004(2) 07/23/2012 Common Shares
27,000
  27,000
D
 
Common Share Option $ 16.12           08/10/2005(4) 07/18/2013 Common Shares
30,000
  30,000
D
 
Common Share Option $ 18.75           02/15/2005(3) 07/16/2014 Common Shares
26,000
  26,000
D
 
Common Share Option $ 15.05           10/04/2007(2) 10/03/2015 Common Shares
10,000
  10,000
D
 
Performance Award Unit $ 0           09/30/2008 02/01/2012 Common Shares
7,700 (5)
  7,700 (5)
D
 
Common Share Option $ 14           01/30/2009(2) 01/30/2017 Common Shares
10,000
  10,000
D
 
Performance Award Unit $ 0           09/30/2009 02/01/2012 Common Shares
7,700 (5)
  7,700 (5)
D
 

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
PESEC JOHN A
KEITHLEY INSTRUMENTS, INC.
28775 AURORA ROAD
SOLON, OH 44139		       VP Worldwide Sales & Support  

Signatures

Mark J. Plush, Attorney-in Fact 10/26/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Acquired through Employee Stock Purchase and Dividend Reinvestment Plan.
(2) Date reported applies to 50% of total, one-half of the balance is then exercisable in each succeeding year
(3) Option became fully vested on February 15, 2005
(4) Option became fully vested on August 10, 2005
(5) Each Performance Award Unit represents the right to receive one common share at the end of the applicable performance period. The number of units actually earned is subject to adjustment based upon the Company's revenue growth versus that of a defined Peer Group, as well as the Company maintaining an acceptable level of profitability. Minimum number of units is 0 while the maximum number of units is two times the target number shown.

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