Filed
pursuant to Rule 424(b)(3)
Registration
Statement File No. 333-132296
PROSPECTUS
SUPPLEMENT NO. 4
TO
PROSPECTUS
DATED APRIL 25, 2007
MDWERKS,
INC.
This
prospectus supplement should be read in conjunction with our prospectus dated
April
25,
2007 and in particular “Risk Factors” beginning on page 7 of the prospectus.
This
prospectus supplement includes the attached Current Report on Form 8-K of
MDwerks, Inc.,
filed
with the Securities and Exchange Commission on September 5, 2007.
The
date
of this prospectus supplement is September 5, 2007