SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report: February 13, 2009

PURE BIOSCIENCE
(Exact name of registrant as specified in its charter)

California
33-0530289
(State or other jurisdiction
of incorporation or organization)
(I.R.S. Employer
Identification No.)

1725 Gillespie Way, El Cajon, California 92020
(Address of principal executive offices)(Zip Code)

(619) 596 8600
(Registrant's telephone number, including area code)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)


Item 5.02    Departure of Directors of Principal Officers; Election of Directors; Appointment of Principal Officers; Compensatory Arrangements of Certain Officers.

On February 13, 2009, Murray Gross resigned as a director of Pure Bioscience. Mr. Gross was a member of the Audit and Compensation Committees of Pure Bioscience. Mr. Gross resigned in order to address business concerns unrelated to Pure Bioscience requiring greater time and attention.  Mr. Gross’ resignation was not the result of any disagreement with respect to the company’s policies, practices or operations. The Board of directors has expressed its gratitude and appreciation for the service to the Corporation by Mr. Gross.

The registrant has provided Mr. Gross with a copy of this current report prior to the filing thereof and informed him that he had the opportunity to provide the registrant with correspondence stating whether he agrees or disagrees with the disclosure contained in this current report which the registrant would also file such correspondence as an exhibit to this current report or an amendment thereto.

Item 9.01.     Financial Statements and Exhibits

(d)     The following exhibits are filed with this report:

Exhibit
Number
Description

17.1 Resignation of Murray Gross dated February 13, 2009




SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

PURE BIOSCIENCE

Dated: February 20, 2009

/s/ Michael L. Krall
Michael L. Krall, Chief Executive Officer