Washington, D.C. 20549

FORM 12b-25


(Check one):


ý Form 10-K

o Form 20-F

o Form 11-K

o Form 10-Q

o Form N-SAR

o Form N-CSR



For Period Ended: December 31, 2004

    o Transition Report on Form 10-K  
    o Transition Report on Form 20-F  
    o Transition Report on Form 11-K  
    o Transition Report on Form 10-Q  
    o Transition Report on Form N-SAR  



For the Transition Period Ended:




Nothing in this form shall be construed to imply that the Commission has
verified any information contained herein.









If the notification relates to a portion of the filing checked above, identify the Item(s) to which the notification relates:  




Bruker BioSciences Corporation

Full Name of Registrant


Bruker Daltonics Inc.

Former Name if Applicable


40 Manning Road

Address of Principal Executive Office (Street and Number)


Billerica, Massachusetts 01821

City, State and Zip Code


PART II — RULES 12b-25(b) AND (c)

If the subject report could not be filed without unreasonable effort or expense and the registrant seeks relief pursuant to Rule 12b-25(b), the following should be completed. (Check box if appropriate)





The reason described in reasonable detail in Part III of this form could not be eliminated without unreasonable effort or expense;
ý   (b)   The subject annual report, semi-annual report, transition report on Form 10-K, Form 20-F, Form 11-K, Form N-SAR or Form N-CSR, or portion thereof, will be filed on or before the fifteenth calendar day following the prescribed due date; or the subject quarterly report or transition report on Form 10-Q, or portion thereof, will be filed on or before the fifth calendar day following the prescribed due date; and
    (c)   The accountant's statement or other exhibit required by Rule 12b-25(c) has been attached if applicable.


State below in reasonable detail why Forms 10-K, 20-F, 11-K, 10-Q, N-SAR, N-CSR, or the transition report or portion thereof, could not be filed within the prescribed time period.

        The Registrant cannot timely file its Annual report on Form 10-K for the year ended December 31, 2004 due to reasons that could not be eliminated without unreasonable effort or expense. The Sarbanes-Oxley Act of 2002 (the "Act") imposed many requirements regarding corporate governance and financial reporting. One requirement under Section 404 of the Act, beginning with this Annual Report, is for management to report on the Registrant's internal control over financial reporting and for our independent registered public accountants, Ernst & Young LLP, to attest to this report. Due in part to the Registrant's substantial effort dedicated to internal control reporting and despite diligent efforts on the part of the Registrant, the work necessary to complete the Registrant's Annual Report on Form 10-K for the year ended December 31, 2004, could not be finished in sufficient time to permit the timely filing of the Form 10-K. Management anticipates that the Annual Report on Form 10-K will be filed on or before March 31, 2005.

(Attach extra Sheets if Needed)

SEC 1344 (07-03)




(1)   Name and telephone number of person to contact in regard to this notification



William J. Knight




(Area Code)
(Telephone Number)







(2)   Have all other periodic reports required under Section 13 or 15(d) of the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of 1940 during the preceding 12 months or for such shorter period that the registrant was required to file such report(s) been filed? If answer is no, identify report(s).







ý Yes        o No



(3)   Is it anticipated that any significant change in results of operations from the corresponding period for the last fiscal year will be reflected by the earnings statements to be included in the subject report or portion thereof?
            o Yes        ý No
    If so, attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate, state the reasons why a reasonable estimate of the results cannot be made.








        Bruker BioSciences Corporation
(Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned hereunto duly authorized.

Date March 16, 2005




        /s/ William J. Knight
William J. Knight
Chief Financial Officer

INSTRUCTION: The form may be signed by an executive officer of the registrant or by any other duly authorized representative. The name and title of the person signing the form shall be typed or printed beneath the signature. If the statement is signed on behalf of the registrant by an authorized representative (other than an executive officer), evidence of the representative's authority to sign on behalf of the registrant shall be filed with the form.


Intentional misstatements or omissions of fact
constitute Federal Criminal Violations
(See 18 U.S.C. 1001).