UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM CORRESPONDENCE PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 September 24, 2004 ------------------ (Date of the earliest event reported) Simulations Plus, Inc. ---------------------- (Exact name of Registrant as specified in its charter) California 95-4595609 ---------- ---------- (State or other jurisdiction (I.R.S. Employer of incorporation) Identification No.) 1-32046 ------- (Commission File Number) 1220 West Avenue J, Lancaster, California 93534 ----------------------------------------------- (Address of principal executive offices) (Zip Code) (661) 723-7723 -------------- Registrant's telephone number, including area code SUPPLIMENTAL RESPONSE TO COMMISSIONERS September 23, 2004 Security and Exchange Commission Washington, D.C. 20549 Commissioners: In response to your comments, Simulations Plus, Inc. acknowledges that; 1. Simulations Plus, Inc. is responsible for the adequacy and accuracy of the disclosure in the filings; 2. Staff comments or changes to disclosure in response to staff comments in the filings reviewed by the staff do not foreclose the Commission from taking any action with respect to the filing; and 3. Simulations Plus, Inc. may not assert staff comments as a defense in any proceeding initiated by the Commission or any person under the federal securities laws of the United States. /s/ Momoko Beran -------------------------------- Momoko Beran Chief Financial Officer